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KMID : 0390220220330040241
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Journal of Clinical Otolaryngology, Head and Neck Surgery
2022 Volume.33 No. 4 p.241 ~ p.245
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A Case of Subglottic Undifferentiated Pleomorphic Sarcoma
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Park Hee-Jun
Lee Dong-Won
Kim Jeong-Kyu
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Abstract
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Undifferentiated pleomorphic sarcoma (UPS) is rare type of soft tissue sarcomas that occur in all parts of body but mostly in the extremities. Sixty -year-old woman presented dyspnea and stridor with benign looking subglottic mass on laryngoscope. Endoscopic laser surgery was performed and histopathology showed diffuse proliferation of pleomorphic plump and spindle cells with no particular orientation to vessels. In immunochemistry, the tumor cells were positive for vimentin, CD68, Ki-67 and negative for Melan A, leukocyte common antigen, CK, S-100, smooth muscle actin, CD1a, CD21, CD23, CD34, D2-40. The patient was finally diagnosed with UPS and underwent postoperative radiotherapy. She was followed for 1 year without recurrence and metastasis. We stress that if a benign looking subglottic mass is accompanied by dyspnea, the possibility of malignancy should be considered and UPS could be included in the differential diagnosis.
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KEYWORD
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Soft tissue neoplasm, Histiocytoma, malignant fibrous, Sarcoma, Larynx
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